Biotechnology Research

smartbax

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At smartbax, we aim to introduce the next generation of antibiotics**.** We develop novel antibacterial compounds with extraordinary potency against multi-drug resistant bacteria and hijack bacterial pathways that no other drug has touched before. As a start-up in Munich’s vibrant biotech scene, we offer an environment where your work makes a real difference. Help us pioneer new therapies that will save lives. 
We are looking for a Senior Scientist (PhD) with expertise in structural biology and data science, full-time, starting immediately, to join our growing team.
<h2>Tasks</h2>
<ul>
<li>Structure-guided optimisation of small molecule antibiotic candidates through both in silico and experimental analyses</li>
<li>Docking and molecular modelling studies to inform medicinal chemistry decision making</li>
<li>Co-crystallization experiments with test compounds and target enzymes</li>
<li>Coordination with CROs</li>
<li>Implementation of AI and machine learning approaches for data analysis, compound design and property prediction</li>
<li>Data evaluation, visualisation and presentation towards the team, shareholders and investors</li>
<li>Creative and critical thinking in solving scientific problems</li>
</ul>
<h2>Requirements</h2>
<ul>
<li>PhD in structural biology, computational chemistry or related subjects</li>
<li>Experience in working with proteins and analysing small molecule-protein interactions </li>
<li>Strong computational and programming skills, including docking, molecular dynamics, machine learning and AI</li>
<li>Additional expertise in handling S2 bacteria is considered a plus</li>
<li>Self-organised, enjoys working in small teams</li>
<li>Creative, fast-thinking and decisive mind who likes tackling challenges</li>
<li>Proficient in written and spoken English; German skills are a plus</li>
</ul>
<h2>Benefits</h2>
<ul>
<li>Purpose: Contribute to the fight against antimicrobial resistance, one of the greatest healthcare challenges of our time</li>
<li>Freedom and agility: Flat hierarchy, fast decision making, and no unnecessary bureaucracy, allowing you to focus on things that really matter</li>
<li>Shaping the company’s future: Responsible position with direct impact and room for creativity in a highly motivated and experienced team</li>
<li>A workplace tailored to your needs: 40 hours per week with flexible start and end times, brand-new lab and office spaces, and the freedom to work from home when needed</li>
<li>Attractive benefits: Monthly vouchers for personal use (e.g. groceries, wellness, etc)</li>
<li>Step into the future of biotech: Join a cutting-edge biotech start-up in Munich, driving innovative drug development with strong venture capital support</li>
</ul>
Start: Immediately | Location: Munich/Neuherberg (Life Science Factory at the Helmholtz Pioneer Campus)
Interested to join the smartbax team? We look forward to receiving your application with a short cover letter, CV and availability.

Senior Scientist - Structural Biology and Data Science (m/w/d)

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