Research Associate, Experimental Immunology
About the Botnar Institute of Immune Engineering
The Botnar Institute of Immune Engineering (BIIE) is a newly founded non-profit research organization aiming to become a world leading research institute for the advanced study of immunological systems with a mission to develop translational solutions for the diagnosis, treatment and prevention of disease.
The scientific foundation of the BIIE and the broader field of Immune Engineering is based on the intersection of three interdisciplinary subdomains: (i) systems immunology, (ii) synthetic immunology and (iii) computational immunology. The BIIE will serve as a hub for multidisciplinary science, by uniting people with diverse expertise in immunology, biomedicine, bioengineering, systems and synthetic biology, computational biology, artificial intelligence and machine learning. As part of the mission of BIIE to make a lasting impact, it will dedicate significant efforts in training early-stage researchers in this unique multidisciplinary environment, thus enabling them to become future leaders in Immune Engineering.
Tasks
About the Experimental Immunology Research Associate - Basel, Switzerland
We are seeking motivated Experimental Immunology Research Associates to join our dynamic research team. The ideal candidate will have a solid background in molecular biology and experimental immunology, with hands-on experience in flow cytometry, sequencing library preparation or monoclonal antibody production. This role involves designing, developing, and optimizing high-dimensional flow cytometry panels, repertoire sequencing protocols and antibody production for the purpose of profiling human immunogenomic diversity.
Principal Responsibilities
- Produce and characterize proteins for immunizations.
- Perform preclinical immunization experiments in murine models.
- Design and optimize isolation of antigen-specific B cells from human and mice
- Analyze and interpret experimental data, maintaining detailed records of experiments and outcomes.
- Contribute to the development of new technologies and methodologies to improve high-throughput antibody discovery.
- Prepare technical reports, summaries, protocols, and quantitative analyses.
- Present findings to team members and contribute to scientific discussions within the group.
Requirements
Desired Qualifications and Skills
- Bachelor’s or Master’s degree in Molecular Biology, Biochemistry, Chemical Engineering, or related field.
- Experience with flow cytometry and cell sorting
- Experience with rodent experiments.
- FELASA certification and accompanying education in accordance with FDHA Ordinance on Training in Animal Husbandry and Handling
- Experience in protein production, purification, and characterization.
- Strong organizational skills with the ability to manage multiple projects simultaneously.
- Excellent problem-solving abilities and attention to detail.
- Effective communication skills, both written and verbal.
- Ability to work both independently and collaboratively in a team-oriented environment.
